It is very important to evaluate the pattern of predominant microorganisms and their antimicrobial susceptibility in new established hospitals. The recognition of changes in antimicrobial susceptibility pattern is a reliable guide for selecting
proper
antibiotics.
I evaluated the distribution of microorganisms and the pattern of antimicrobial susceptibility on 3,583 clinical isolated at Ewha Womans University Mokdong Hospital from September 1993 to August 1994. The pattern of antibiotic susceptibility was
also
compared between two periods(Sep., 1993-Feb., 1994 and March 1994-Aug., 1994).
@ES The results were as follows:
@EN 1) The total isolation rate was 20.3% (3.247 specimens were cultured from 15,979 specimens requested).
2) The most commonly isolated microorganisms were E. coli. Staphylococcus aureus, Pseudomonas aeruginosa, Staphylococcus epidermidis, and Entercoccus faecalis in decreasing rate.
3) E. coli was highly resistant to ampicillin, piperacillin and revealed over 50% sensitivity to cephalothin, gentamicin and tobramycin.
4) Pseudomonas aeruginosa was highly resistant to ampicillin, cephalothin and revealed over 70% sensitivity to ceftazidime, amikacin, gentamicin, tobramycin, ciprofloxacin and piperacillin.
5) Staphylococcus aureus was highly resistant to ampicillin, penicillin and revealed about50% sensitivity to oxacillin, cephalothin and clindamycin. The susceptibility pattern of Staphylococcus epidermis was slightly different.
6) The sensitivity of penicillin of Enterococcus faecalis is 60% and that of Strepococcus pneumoniae was 71%.
7) The antimicrobial susceptibility of Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae were slightly decreased during last 6 months.
There were some differences of the distribution of microorganisms and their antimicrobial susceptibility pattern on isolates of this study with comparison of other reports in Korea. Antimicrobial susceptibility pattern showed slightly increase of
resistant strains. This study suggested that the periodic evaluation of antimicrobial susceptibility pattern was desirable.
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